Find information about common, infrequent and rare side effects of Wellbutrin XL Oral. Note: This document contains side effect information about bupropion. Some of the dosage forms listed on this page may not apply to the brand name Wellbutrin. Effect of Antidepressants on Sex Hormone Levels and Sexual Functioning The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Serotonin may affect the menstrual cycle by stimulating secretion of specific hormones, according to a 2002 paper on Venlafaxine-Associated Vaginal Bleeding written by professor Sunny A. Linnebur, Pharm.D., of the University of Colorado School of Pharmacy. Hormones are substances produced by the endocrine glands that have a tremendous effect on bodily processes. The glands in the endocrine system influence growth and development, mood, sexual. Wellbutrin is an antidepressant in the aminoketone class used for the management of major depression and seasonal affective disorder. Wellbutrin is available in generic form. Can Wellbutrin cause Hormonal Changes? Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. Wellbutrin and Armour Thyroid pooh103 Since starting Armour thyroid for the last 4 months or so, I have noticed a need to go down in the levels of Wellbutrin I was taking. I think Wellbutrin is one though that is not supposed to have that side effect. Hopefully between that and the patch you'll get to feeling normal again soon. I wish you luck. Hopefully between that and the patch you'll get to feeling normal again soon. Is an increased sex-drive while on Wellbutrin a common side-effect? Reading all this stuff about Wellbutrin and increased libidos makes me think it's some sort of Viagra.